Organic phosphoric acids and derivatives
Apexbio Technology LLC Rilmenidine Phosphate 85409-38-7 100mg
Rilmenidine phosphate (CAS 85409-38-7) is a water-soluble derivative of rilmenidine that selectively targets imidazoline I1 receptors non-adrenergic high-affinity binding sites implicated in blood pressure regulation Activation of I1 receptors modulates sympathetic outflow resulting in antihypertensive effects observed in both preclinical models and clinical studies In Hep G2 cells rilmenidine attenuates stearic acid-induced lipid accumulation associated with p38 MAPK activation and increased FXR expression In high-fat diet-fed mice rilmenidine ameliorates hepatic steatosis through imidazoline I1 receptor-mediated pathways This compound is of interest for investigating cardiovascular and metabolic disease mechanisms
Apexbio Technology LLC KN-93 Phosphate 1188890-41-6 10mM (in 1mL DMSO)
KN-93 Phosphate (CAS 1188890-41-6) is a small-molecule inhibitor targeting calcium/calmodulin-dependent protein kinase II (CaMKII) It is designed to selectively inhibit CaMKII thereby modulating cellular proliferation survival neurotransmitter regulation and related signal transduction pathways KN-93 Phosphate exerts its biological activity primarily by competitively binding to Ca2 /calmodulin disrupting their interaction with CaMKII and preventing CaMKII activation and autophosphorylation In cell-based studies KN-93 Phosphate demonstrates inhibitory activity with IC50 values of 9 M for CaMKII monomer and 3 M for CaMKII dodecamer Experimental models include hepatic stellate cells and NIH 3T3 fibroblasts Based on these pharmacological properties KN-93 Phosphate holds research potential in the study of cell cycle regulation apoptosis neurotransmitter synthesis and neurodegenerative disorders particularly Parkinson s disease models
Apexbio Technology LLC KN-93 Phosphate 1188890-41-6 10mg
KN-93 Phosphate (CAS 1188890-41-6) is a small-molecule inhibitor targeting calcium/calmodulin-dependent protein kinase II (CaMKII) It is designed to selectively inhibit CaMKII thereby modulating cellular proliferation survival neurotransmitter regulation and related signal transduction pathways KN-93 Phosphate exerts its biological activity primarily by competitively binding to Ca2 /calmodulin disrupting their interaction with CaMKII and preventing CaMKII activation and autophosphorylation In cell-based studies KN-93 Phosphate demonstrates inhibitory activity with IC50 values of 9 M for CaMKII monomer and 3 M for CaMKII dodecamer Experimental models include hepatic stellate cells and NIH 3T3 fibroblasts Based on these pharmacological properties KN-93 Phosphate holds research potential in the study of cell cycle regulation apoptosis neurotransmitter synthesis and neurodegenerative disorders particularly Parkinson s disease models
Sigma Aldrich Fine Chemicals Biosciences BIS 4-NITROPHENYL PHOSPHATE 5G
NC2961995 BIS 4-NITROPHENYL PHOSPHATE 5G
Medchemexpress LLC P-nitrophenyl phosphorylcholine | 21064-69-7 | MFCD00077834 | 99.6% | 304.24 g/mol | C11H17N2O6P | 5 MG
p-Nitrophenyl phosphorylcholine is a chromogenic substrate for measuring phospholipase C (PLC) activity. Enzymatic hydrolysis releases p-nitrophenolate, producing a yellow chromophore that is detectable by spectrophotometry (typically at ~405 nm). The product is supplied with supporting documentation to aid quality control and safe handling.
Medchemexpress LLC Trisodium phosphate | 7601-54-9 | MFCD00003510 | 99.5% | 163.94 g/mol | Na3PO4 | 1kg
Trisodium phosphate is a food additive Trisodium phosphate affects the growth parameters (lag phase maximum growth rate) of Listeria monocytogenes and increases the sensitivity of Gram-negative bacteria to Lysozyme (HY-P1068) and Nisin (HY-P1607)[1][2]
Sigma Aldrich Fine Chemicals Biosciences Amonium phosphate monobas2.5KG
AMMONIUM03 Amonium phosphate monobas2.5KG